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Table 1 Significant transcriptional factors in up-regulated genes from Day 1 to Day 2

From: Uncovering mechanisms of transcriptional regulations by systematic mining of cis regulatory elements with gene expression profiles

Motif

Occurrence Number

p-value

q-value

Transcription Factors

RRCAGGTGNCV

17

3.87E-05

0.00274

E12

SRACAGGTGKYG

23

0.000125

0.00399

MYOD

RSTGACTNMNW

65

0.000253

0.00399

AP1

GGTACAANNTGTYCTK

34

0.000282

0.00399

GRE

GGACATGCCCGGGCATGTCY

170

0.000306

0.00399

P53

GGGGCGGGGT

245

0.000338

0.00399

SP1

NNRYCACGTGRYNN

38

0.000422

0.00426

USF

CTCTAAAAATAACYCY

11

0.000485

0.00429

MEF2

ATGCCCATATATGGWNNT

67

0.000605

0.00475

SRF

GAAAAGYGAAASY

8

0.00178

0.0126

IRF2

AGATADMAGGGA

15

0.0029

0.018

GATA4

CKSNYTAAAAAWRMCY

4

0.00305

0.018

MMEF2

TGACGTYA

49

0.00389

0.0192

CREBP1/CJUN

RGCAGSTG

14

0.00398

0.0192

MYOGENIN

GGGRATTTCC

75

0.0041

0.0192

NFKAPPAB65

  1. Significant transcriptional factors in up-regulated genes from Day 1 to Day 2. The Motif column shows the consensus binding site sequence for the transcriptional factor. The second column lists the total number genes containing that that transcriptional factor binding sites in the promoter regions. The p-value column illustrates the Mann-Whitney rank sum p-value. The q-value column shows the multiple testing corrected FDR q-value. The transcriptional factor column lists the name of the transcriptional factor which is known to bind to that motif. The total number of up-regulated Refseq genes with raw expression levels at least 100 in Day 2 is 3338.
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BioData Mining

ISSN: 1756-0381