Skip to main content

Table 2 Significant transcriptional factors in down-regulated genes from Day 1 to Day 2

From: Uncovering mechanisms of transcriptional regulations by systematic mining of cis regulatory elements with gene expression profiles

Motif

Occurrence Number

p-value

q-value

Transcription Factors

NKTSSCGC

116

4.47E-11

3.97E-09

E2F1

RACCACGTGCTC

351

2.31E-07

1.03E-05

MYC/MAX

GGGGCGGGGT

253

2.64E-06

7.82E-05

SP1

ARATKGAST

14

6.73E-06

0.000149

FOXM1

TRRCCAATSRN

95

1.56E-05

0.000278

NFY

NNCCACGTGNNN

12

0.000292

0.00415

NMYC

GGACATGCCCGGGCATGTCY

205

0.000327

0.00415

P53

TGACGTYA

65

0.000496

0.00551

CREBP1/CJUN

NBTGGGTGGTCN

12

0.00142

0.014

GLI

NNNNNCCATNTWNNNWN

64

0.00248

0.02

YY1

GCHCDAMCCAG

5

0.00916

0.0592

CP2

TGCTGAGTCAY

5

0.00945

0.0592

NFE2

TCATGTGN

9

0.0124

0.0675

TFE

TGACGTMA

90

0.0136

0.0675

CREB

TWSGCGCGAAAAYKR

10

0.0141

0.0675

E2F

  1. Significant transcriptional factors in down-regulated genes from Day 1 to Day 2. The Motif column shows the consensus binding site sequence for the transcriptional factor. The second column lists the total number of genes containing that motif in the promoter regions. The p-value column illustrates the Mann-Whitney rank sum p-value. The q-value column shows the multiple testing corrected FDR q-value. The last column lists the name of the transcription factor. The total number of down-regulated Refseq genes with raw expression levels at least 100 in Day 1 is 3728.