Skip to main content

Table 2 Combinatorial clusters of chromatin-bound TFs most significantly associated with p65 recruitment

From: Genome-wide predictors of NF-κB recruitment and transcriptional activity

cluster

log-odds

p-value

supp.

conf.

creb1-foxa2-jund-rad21

3.20

1.4E-11

7890

0.76

creb1-rad21-usf1-yy1

2.56

1.4E-09

5815

0.67

foxa2-rad21-usf1-yy1

2.03

9.1E-07

5672

0.59

gata3-tcf12-usf1

−4.66

1.1E-08

12907

0.01

creb1-rad21-sp1

2.90

1.4E-26

9415

0.72

max-rad21-sp1

2.74

4.6E-15

10061

0.70

creb1-foxa2-yy1

2.52

1.7E-14

11814

0.67

creb1-max-rad21

2.49

3.6E-87

11088

0.65

creb1-rad21-tcf12

2.49

1.1E-11

8507

0.66

max-rad21-tcf12

2.44

2.6E-09

9096

0.65

creb1-foxa2-sp1

2.35

4.8E-10

18956

0.64

jund-max-rad21

2.24

6.3E-10

9186

0.62

foxa2-max-sp1

2.13

1.8E-06

20425

0.60

gr-max-rad21

2.11

2.8E-12

9346

0.60

jund-pol2-rad21

2.08

7.6E-06

6302

0.60

cebpb-jund-rad21

2.01

6.5E-07

6442

0.58

max-pol2-rad21

2.00

4.5E-17

7741

0.58

cebpb-foxa2-yy1

1.95

2.9E-05

7025

0.58

elf1-foxa2-rad21

1.71

1.9E-08

4304

0.53

foxa2-max-yy1

1.62

4.2E-05

11994

0.52

cebpb-foxa2-usf1

0.90

6.6E-05

12804

0.39

  1. TF-clusters obtained by the TGC algorithm at stage 2 TSS-distal sites. Each cluster is significantly enriched (or depleted) for p65 binding events. The enrichment log-odds and significance are from the Fisher’s exact test. Support (supp.) and confidence (conf.) are calculated genome-wide for all regulatory sites. Support is the number of sites occupied by all TFs from a TF-cluster, confidence is the percentage of these sites that will recruit p65