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Table 2 Comparison of estimated prior probability with true ratio in the simulation study

From: A novel joint analysis framework improves identification of differentially expressed genes in cross disease transcriptomic analysis

DE

status

X

600

700

800

900

1000

Estimate

Truth

Estimate

Truth

Estimate

Truth

Estimate

Truth

Estimate

Truth

(0,0)

0.8857 (0.006)a

0.86

0.8914 (0.006)

0.87

0.8982 (0.006)

0.88

0.9054 (0.005)

0.89

0.9068 (0.003)

0.9

(0,1)

0.041 (0.005)

0.04

0.0356 (0.005)

0.03

0.0284 (0.004)

0.02

0.0218 (0.003)

0.01

0.018 (0.003)

0

(1,0)

0.042 (0.008)

0.04

0.0365 (0.008)

0.03

0.0316 (0.006)

0.02

0.0258 (0.003)

0.01

0.02 (0.004)

0

(1,1)

0.031 (0.003)

0.06

0.0364 (0.002)

0.07

0.0417 (0.004)

0.08

0.0469 (0.005)

0.09

0.0546 (0.004)

0.1

  1. a The values in the parentheses represent the standard deviation summarized from 10 repeated runs